donepezil
DRUGEvidence in r/alzheimers — Alzheimer's
Trend support
- Current seven-day window
- Current 2026-09-22 → 2026-09-28
- Comparison seven-day window
- Comparison 2026-09-15 → 2026-09-21
- Distinct-document support
- Seen in 10 current vs 2 comparison posts/comments
- Mentions
- 11 current vs 4 mentions
Windows are complete UTC days compared with the preceding seven. How trends are measured.
Also Mentioned 22 times in the most-discussed range 2026-08-30 → 2026-09-29 — frequency, not a trend.
Attention over time
7-day rolling share of analyzed posts/comments mentioning this entity · 90 daily points ending 2026-09-28
Final complete day: 2026-09-28. Attention was 1.0% — this entity appeared in 10 of 988 analyzed posts/comments in the seven days ending that day (11 mentions).
Hover, touch, or focus the chart (Tab) and use the arrow keys — each point is one seven-day window.
View all 90 data points (semantic table)
| Week ending | Seven-day range | Status | Prevalence | Seen in | Mentions | Analyzed |
|---|---|---|---|---|---|---|
| 2026-07-01 | 2026-06-25 → 2026-07-01 | Comparable | 0.0% | 0 of 391 | 0 | 391 |
| 2026-07-02 | 2026-06-26 → 2026-07-02 | Comparable | 0.0% | 0 of 415 | 0 | 415 |
| 2026-07-03 | 2026-06-27 → 2026-07-03 | Comparable | 0.0% | 0 of 394 | 0 | 394 |
| 2026-07-04 | 2026-06-28 → 2026-07-04 | Comparable | 0.0% | 0 of 430 | 0 | 430 |
| 2026-07-05 | 2026-06-29 → 2026-07-05 | Comparable | 0.0% | 0 of 446 | 0 | 446 |
| 2026-07-06 | 2026-06-30 → 2026-07-06 | Comparable | 0.0% | 0 of 484 | 0 | 484 |
| 2026-07-07 | 2026-07-01 → 2026-07-07 | Comparable | 0.0% | 0 of 547 | 0 | 547 |
| 2026-07-08 | 2026-07-02 → 2026-07-08 | Comparable | 0.3% | 2 of 588 | 2 | 588 |
| 2026-07-09 | 2026-07-03 → 2026-07-09 | Comparable | 0.5% | 3 of 600 | 3 | 600 |
| 2026-07-10 | 2026-07-04 → 2026-07-10 | Comparable | 0.5% | 3 of 617 | 3 | 617 |
| 2026-07-11 | 2026-07-05 → 2026-07-11 | Comparable | 0.5% | 3 of 630 | 3 | 630 |
| 2026-07-12 | 2026-07-06 → 2026-07-12 | Comparable | 0.5% | 3 of 634 | 3 | 634 |
| 2026-07-13 | 2026-07-07 → 2026-07-13 | Comparable | 0.8% | 5 of 656 | 5 | 656 |
| 2026-07-14 | 2026-07-08 → 2026-07-14 | Comparable | 0.8% | 5 of 606 | 5 | 606 |
| 2026-07-15 | 2026-07-09 → 2026-07-15 | Comparable | 0.7% | 4 of 551 | 4 | 551 |
| 2026-07-16 | 2026-07-10 → 2026-07-16 | Comparable | 1.3% | 8 of 602 | 9 | 602 |
| 2026-07-17 | 2026-07-11 → 2026-07-17 | Comparable | 1.6% | 10 of 635 | 11 | 635 |
| 2026-07-18 | 2026-07-12 → 2026-07-18 | Comparable | 2.1% | 12 of 585 | 13 | 585 |
| 2026-07-19 | 2026-07-13 → 2026-07-19 | Comparable | 2.1% | 13 of 610 | 14 | 610 |
| 2026-07-20 | 2026-07-14 → 2026-07-20 | Comparable | 1.7% | 11 of 635 | 12 | 635 |
| 2026-07-21 | 2026-07-15 → 2026-07-21 | Comparable | 1.6% | 11 of 689 | 12 | 689 |
| 2026-07-22 | 2026-07-16 → 2026-07-22 | Comparable | 1.3% | 10 of 785 | 11 | 785 |
| 2026-07-23 | 2026-07-17 → 2026-07-23 | Comparable | 0.8% | 6 of 724 | 6 | 724 |
| 2026-07-24 | 2026-07-18 → 2026-07-24 | Comparable | 0.6% | 4 of 669 | 4 | 669 |
| 2026-07-25 | 2026-07-19 → 2026-07-25 | Comparable | 0.3% | 2 of 676 | 2 | 676 |
| 2026-07-26 | 2026-07-20 → 2026-07-26 | Comparable | 0.2% | 1 of 665 | 1 | 665 |
| 2026-07-27 | 2026-07-21 → 2026-07-27 | Comparable | 0.2% | 1 of 618 | 1 | 618 |
| 2026-07-28 | 2026-07-22 → 2026-07-28 | Comparable | 0.2% | 1 of 629 | 1 | 629 |
| 2026-07-29 | 2026-07-23 → 2026-07-29 | Comparable | 0.2% | 1 of 562 | 1 | 562 |
| 2026-07-30 | 2026-07-24 → 2026-07-30 | Comparable | 0.0% | 0 of 620 | 0 | 620 |
| 2026-07-31 | 2026-07-25 → 2026-07-31 | Comparable | 0.0% | 0 of 689 | 0 | 689 |
| 2026-08-01 | 2026-07-26 → 2026-08-01 | Comparable | 0.0% | 0 of 766 | 0 | 766 |
| 2026-08-02 | 2026-07-27 → 2026-08-02 | Comparable | 0.0% | 0 of 762 | 0 | 762 |
| 2026-08-03 | 2026-07-28 → 2026-08-03 | Comparable | 0.0% | 0 of 752 | 0 | 752 |
| 2026-08-04 | 2026-07-29 → 2026-08-04 | Comparable | 0.5% | 4 of 758 | 5 | 758 |
| 2026-08-05 | 2026-07-30 → 2026-08-05 | Comparable | 1.0% | 8 of 812 | 10 | 812 |
| 2026-08-06 | 2026-07-31 → 2026-08-06 | Comparable | 1.5% | 12 of 811 | 14 | 811 |
| 2026-08-07 | 2026-08-01 → 2026-08-07 | Comparable | 1.5% | 12 of 786 | 14 | 786 |
| 2026-08-08 | 2026-08-02 → 2026-08-08 | Comparable | 1.9% | 14 of 726 | 16 | 726 |
| 2026-08-09 | 2026-08-03 → 2026-08-09 | Comparable | 2.0% | 15 of 767 | 17 | 767 |
| 2026-08-10 | 2026-08-04 → 2026-08-10 | Comparable | 1.9% | 15 of 796 | 17 | 796 |
| 2026-08-11 | 2026-08-05 → 2026-08-11 | Comparable | 1.5% | 11 of 738 | 12 | 738 |
| 2026-08-12 | 2026-08-06 → 2026-08-12 | Comparable | 1.1% | 7 of 643 | 7 | 643 |
| 2026-08-13 | 2026-08-07 → 2026-08-13 | Comparable | 0.6% | 3 of 506 | 3 | 506 |
| 2026-08-14 | 2026-08-08 → 2026-08-14 | Comparable | 0.7% | 3 of 424 | 3 | 424 |
| 2026-08-15 | 2026-08-09 → 2026-08-15 | Comparable | 0.3% | 1 of 358 | 1 | 358 |
| 2026-08-16 | 2026-08-10 → 2026-08-16 | Comparable | 0.0% | 0 of 225 | 0 | 225 |
| 2026-08-17 | 2026-08-11 → 2026-08-17 | Comparable | 0.0% | 0 of 120 | 0 | 120 |
| 2026-08-18 | 2026-08-12 → 2026-08-18 | Low coverage | — | — | 0 | 53 |
| 2026-08-19 | 2026-08-13 → 2026-08-19 | Low coverage | — | — | 0 | 0 |
| 2026-08-20 | 2026-08-14 → 2026-08-20 | Low coverage | — | — | 0 | 0 |
| 2026-08-21 | 2026-08-15 → 2026-08-21 | Low coverage | — | — | 0 | 0 |
| 2026-08-22 | 2026-08-16 → 2026-08-22 | Low coverage | — | — | 0 | 0 |
| 2026-08-23 | 2026-08-17 → 2026-08-23 | Low coverage | — | — | 0 | 0 |
| 2026-08-24 | 2026-08-18 → 2026-08-24 | Low coverage | — | — | 0 | 0 |
| 2026-08-25 | 2026-08-19 → 2026-08-25 | Low coverage | — | — | 0 | 0 |
| 2026-08-26 | 2026-08-20 → 2026-08-26 | Low coverage | — | — | 0 | 0 |
| 2026-08-27 | 2026-08-21 → 2026-08-27 | Low coverage | — | — | 0 | 0 |
| 2026-08-28 | 2026-08-22 → 2026-08-28 | Low coverage | — | — | 0 | 0 |
| 2026-08-29 | 2026-08-23 → 2026-08-29 | Low coverage | — | — | 0 | 0 |
| 2026-08-30 | 2026-08-24 → 2026-08-30 | Low coverage | — | — | 0 | 20 |
| 2026-08-31 | 2026-08-25 → 2026-08-31 | Comparable | 0.0% | 0 of 127 | 0 | 127 |
| 2026-09-01 | 2026-08-26 → 2026-09-01 | Comparable | 0.5% | 1 of 202 | 1 | 202 |
| 2026-09-02 | 2026-08-27 → 2026-09-02 | Comparable | 1.1% | 3 of 280 | 3 | 280 |
| 2026-09-03 | 2026-08-28 → 2026-09-03 | Comparable | 0.8% | 3 of 365 | 3 | 365 |
| 2026-09-04 | 2026-08-29 → 2026-09-04 | Comparable | 0.7% | 3 of 432 | 3 | 432 |
| 2026-09-05 | 2026-08-30 → 2026-09-05 | Comparable | 0.8% | 4 of 528 | 4 | 528 |
| 2026-09-06 | 2026-08-31 → 2026-09-06 | Comparable | 0.8% | 5 of 642 | 5 | 642 |
| 2026-09-07 | 2026-09-01 → 2026-09-07 | Comparable | 0.8% | 5 of 630 | 5 | 630 |
| 2026-09-08 | 2026-09-02 → 2026-09-08 | Comparable | 0.6% | 4 of 627 | 4 | 627 |
| 2026-09-09 | 2026-09-03 → 2026-09-09 | Comparable | 0.3% | 2 of 629 | 2 | 629 |
| 2026-09-10 | 2026-09-04 → 2026-09-10 | Comparable | 0.6% | 4 of 677 | 4 | 677 |
| 2026-09-11 | 2026-09-05 → 2026-09-11 | Comparable | 0.6% | 4 of 700 | 4 | 700 |
| 2026-09-12 | 2026-09-06 → 2026-09-12 | Comparable | 0.4% | 3 of 689 | 3 | 689 |
| 2026-09-13 | 2026-09-07 → 2026-09-13 | Comparable | 0.3% | 2 of 650 | 2 | 650 |
| 2026-09-14 | 2026-09-08 → 2026-09-14 | Comparable | 0.3% | 2 of 663 | 2 | 663 |
| 2026-09-15 | 2026-09-09 → 2026-09-15 | Comparable | 0.3% | 2 of 672 | 2 | 672 |
| 2026-09-16 | 2026-09-10 → 2026-09-16 | Comparable | 0.3% | 2 of 700 | 2 | 700 |
| 2026-09-17 | 2026-09-11 → 2026-09-17 | Comparable | 0.0% | 0 of 655 | 0 | 655 |
| 2026-09-18 | 2026-09-12 → 2026-09-18 | Comparable | 0.0% | 0 of 638 | 0 | 638 |
| 2026-09-19 | 2026-09-13 → 2026-09-19 | Comparable | 0.2% | 1 of 612 | 1 | 612 |
| 2026-09-20 | 2026-09-14 → 2026-09-20 | Comparable | 0.2% | 1 of 630 | 1 | 630 |
| 2026-09-21 | 2026-09-15 → 2026-09-21 | Comparable | 0.3% | 2 of 707 | 4 | 707 |
| 2026-09-22 | 2026-09-16 → 2026-09-22 | Comparable | 0.6% | 5 of 785 | 8 | 785 |
| 2026-09-23 | 2026-09-17 → 2026-09-23 | Comparable | 0.7% | 6 of 925 | 9 | 925 |
| 2026-09-24 | 2026-09-18 → 2026-09-24 | Comparable | 0.8% | 8 of 971 | 11 | 971 |
| 2026-09-25 | 2026-09-19 → 2026-09-25 | Comparable | 0.8% | 8 of 1,018 | 11 | 1,018 |
| 2026-09-26 | 2026-09-20 → 2026-09-26 | Comparable | 0.9% | 9 of 1,059 | 12 | 1,059 |
| 2026-09-27 | 2026-09-21 → 2026-09-27 | Comparable | 0.8% | 9 of 1,104 | 12 | 1,104 |
| 2026-09-28 | 2026-09-22 → 2026-09-28 | Comparable | 1.0% | 10 of 988 | 11 | 988 |
Each point is a seven-day rolling window of complete UTC days; a point is comparable only when at least 100 analyzed posts or comments fall inside it. A day with no analyzed records counts as zero; missing coverage is marked and never shown as zero. The series ends at the latest complete analyzed day — it never extends into the current incomplete day. How attention is measured.
Recent mentions
- Comment
Thank you for reply. I found the donepezil helped a little in the first couple of weeks (accompanied by vivid dreams, which have now ceased). I am due to double the dosage shortly. Based on my experience, I expect marginal improvement with an increased dosage, but time-limited to some weeks. I’ll ask about adding memantine whenever the neurologist calls me in again- perhaps in six months.
- Comment
Thanks for sharing. I'm sorry to hear that donepezil wasn't effective for you. Did you try increasing the dose? I've started it but don't feel anything from it yet. It has only been about 2 weeks so the verdict is still out. My neuro spoke of adding memantine if needed. I'm scheduled to meet with what the University of Chicago calls a "memory specialist" in mid-November to determine whether infusions might help. Time will tell.
- Comment
My mom was loosing her appetite and weight(128 to 102) due to appetite issue with donepezil, after much research I found that there was an appetite stimulant pill called mirtazapine, after a few months at 30 mg, she's eating me out of house at home, this past months weigh in is the first weight gain (+4) in 2 years.
- Comment
Is she on Donepezil or aricept? I know those can cause eating issues. Can she have cannabis? Might help with a few things 🤪🙈
- Comment
This is interesting. 6 months ago my neurologist recommended the Benfotamine supplement for me. He said he was taking it and it helped with the “ fuzzy cloudiness “ he was experiencing. I’ve been taking 2/day , 300mg. Each = 600mg. per day. I am doing very well mentally and memory wise. I have also been taking Memantine and Donepezil for almost 3 years. My progression has been snail like. I’m doing better now than 3 years ago, and yes, things have changed but I’m still independent and capable of doing daily activities. Why? No clue. But I’ve done everything my neurologist has suggested, educated myself on AD, changed many personal and lifestyle habits and am just thankful for my health. (M75) diagnosed 3 years ago with AD.
Excerpts above are public Reddit posts and comments. WIO never synthesizes Reddit URLs from stored ids, and entities are extracted automatically and may be wrong. See the extraction notes and the limitations and privacy section of the methodology.